Reviewing the Roads of COVID-19 Vaccine Trials

since 1 year all pharmaceutical companies around the globe are working to establish vaccines for the Coronavirus and we have at present 86 Candidate Vaccines, 20 Candidate Vaccines in Stage 3 trials, and 11 authorized vaccines across different countries.
Let us see how far the Pharmaceuticals have travelled so far to fight this virus.
As of 05-02-2021, Results from preliminary trail showed that Johnson & Johnson, single dose vaccine is safe and effective for which the FDA have asked their independent experts to debate the details on February 26.

 On 08-02-2021, South Africa Halted Astra Zeneca Vaccine, for healthcare staffs on the ground that the results of a small trial, which indicate that the vaccine is not effective in preventing mild-to-moderate illness caused by the variant that was now dominant in the country.

As of 09-02-2021, the Navajo Nation was scheduled to receive 29,000 doses of COVID-19 vaccine.
Since the previous result on Astra Zeneca vaccine revealed that it was less effective to SARS-CoV-2 variant in South Africa they replaced this vaccine with Johnson & Johnson vaccines.(10-02-2021)

 Till 19-02-2021, 
  • A recent study investigated the neutralizing effect of the Moderna and Pfizer-BioNTech mRNA vaccines against mutant forms of the spike protein found in some of the recently identified SARS-CoV-2 variants. The scientists found a one- to three-fold decrease in neutralizing activity against the variants.
    *Astra Zeneca announced that it might take 6-9 months to adapt their vaccine against new SARS-CoV-2.

  • Data from the country of Israel said that Pfizer Vaccine has reduced the cases to over50% so far.

  • Astra Zeneca Vaccine was authorized for Emergency use by WHO.

  • US Government Accountability Office report Johnson & Johnson have a short supply of their COVID-19 vaccine candidate.
    *Pfizer announced that they have started trials in pregnant women’s. Also they are seeking permission from the FDA to store the vaccine for up to 2 weeks at 25°C to -15°C (-13°F to 5°F).

    Presently, all the pharmaceutical companies are still conducting trials for the new variant, and hopefully we will soon have effective vaccines in the global market.

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